Link Between Scarlet Fever Preceding The Diagnosis Of Autoimmune Diseases?

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CrappyColon

I'm starting to research this and am asking the same question in other groups and my Drs at Cleveland Clinic who don't mind all my 'jodie' questions.  Has anyone who has been diagnosed with an autoimmune disease had scarlet fever first? (sometimes called scarlatina, it's the rash on the body that can be manifest during strep infections) Most common during childhood years.  

w30bob

Say what????? Frankly Scarlet, I don't give a damn.  Sorry, that just popped into my head.   Scarlatina?......is that the Italian version of Scarlet......or the mini version?  I think I had a distant cousin named Scarlina.................she was my second uncle Vinny's daughter.  Ugly as all hell, but no one would ever tell Vinny.  That's how you'd end up with your knees broken and duct tape over your mouth in the trunk of his Eldorado Barritz on its way to the Hudson river, where your body would be chained to a concrete block and tossed in the river.  He called it 'snorkeling without a snorkel'.  We didn't mess with uncle Vinny.  Or Scarlina.

Sorry, just in a very playful mood this morning. 

Ummm........I think I had diaper rash when I was a kid..............does that count?  

;O)

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eefyjig

I had it as a baby, Jodie. My mom told me that my sister and brother were rarely sick but brought everything home to me and that I was sick for the entire first year of my life. Scarlet fever was one of those illnesses I had.  😬

CrappyColon
Reply to eefyjig

Lori, I had it as a child. Then my daughter had it around the same age- her case was so severe she was hospitalized. 

CrappyColon
Reply to w30bob

Frankly Bob, I think you spelled ‘barritz’ wrong and diaper rash won’t cut it. I’ll wait while you check the spelling. Maybe your ‘uncle’ made up his own spelling of it and no one wanted to correct him?   You’re making this ‘cousin’ and bacterial infection sound like the same Italian small plate 😝 

 
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Mysterious Mose

Yes. My mother had scarlet fever in the 1930s and was diagnosed with multiple sclerosis in 1974. The scarlet fever was often discussed as a potential tipping point for the MS. However, there is also history of auto-immune diseases on her side of the family. So, the scarlet fever may not have had anything to do with it. I suppose it depends on whether or not auto-immune diseases run in families. I think the jury is still out on that.

Daniel

CrappyColon
Reply to Mysterious Mose

Several of the autoimmune diseases have overlapping symptoms and/or seem to be diagnosed alongside another one. As they discover more in gene research/therapy it will be interesting what we learn. 

Morning glory

It will be interesting to read what you find out.

w30bob
Reply to CrappyColon

You're correct Crapster, it's correctly spelled Biarritz, but uncle Vinny said it as Barritz...........and like I told you before.........you don't mess with cousin Vinny.  Becoming catfish fodder because someone mispelled is not a good reason.  Uncle Vinny could have called his car a Cadillac Pretzel and no one would've every say he was wrong.  At least not twice. 

I think you would have liked cousin Vinny!

;O)

Jayne
Reply to w30bob

;-)))

 

 

Jodie,

My Father had scarlet fever as a child - from which he recovered.

Later as a young man during WWII he went out East on active service [with no innoculation of any kind] and came home to UK with severe Colitus, and blackwaterfever - there may have been a connection with his Scarlet fever as a child - but I thought it to be a tenuous one?

I do know that Maleria, was part of his diagnoses and for the rest of his life [He lived to his 83rd year] he always took precautions against mosquitoes [and other midge bites too] - he very fair skinned and stayed out of the heat   [was suseptable to 'sun stroke too'] .......

 

On a more frivilous note, and to lighten my heaviness of writing -  there was a standing joke in our familiy, I used to relate to very much as a child ..... it was one of the 'knock-knock - whos'es there/'  ones .....

"Kock-knock"- 'Who's there?' = "Amos" ..... 'Amos Who?' ........... "A mosquitoe'

 

sorry about that one ......

 

 

After your feedback Jodie, I have come back and edited out my comment concerning my own childhood innoculation - for clearly it DID NOT INCLUDE AN IMMUNISATION AGAINST SCARLET FEVER !]

HOWEVER, - I have looked at the possible modern data regarding autoimmune elements and my Father's 'Blackwater Fever diagnoses and it may appear that a deal of autoimmunity research began after the war according to certain references online.

I did see this: 

 

" The most probable explanation for blackwater fever is an autoimmune reaction apparently caused by the interaction of the malaria parasite and the use of quinine. Blackwater fever is caused by heavy parasitization of red blood cells with Plasmodium falciparumible connection "

[Lots of tonic water used to be drunk in hot waether in the days when it DID

PPS

Jodie, I was also interested to find reference to Altered Bioavailability and Pharmacokinetics in Crohn’s Disease: Capturing Systems Parameters for PBPK to Assist with Predicting the Fate of Orally Administered Drugshave real quinnine - so quinine would have been in the system - but probably only a trace element?]

 

 

 

A deal of autoimmune research seemed to comence around 1945 and post war ... so cases such as my Father's - although poorly defined as Officers who were returned home folliwng active service were not followed up back then. 

 

 

How much of CD has a traceable  'genetic inheritance' remains unclear - and so far as my Paternal ancestry may or may not inform, there was definately Colitus during his latter forty years as a 'managed' condition, by way of careful diet -  of my Father [probably UC]  .....  

I do not know the Grandparent / GGP generation information - so unable to comment further as to any possible info in this regard. 

 

 

When I was first diagnosed with CD as a young woman late teens and had my own 'experimental treatments, as my family chose to delay surgical intervention whre infection was clearly prevalent .... We did not KNOW then,, but I long suspected that Cd had genetic elements involved .... and so, personally made the decision not to have children.

What I have tried to do in my own medical path is always to be open to possibilities and have contributed where I can to R+D and have remainined in touch with my various Clinitiacians.   Perhaps in so doing there may be a slightly more informed line of reference that may inform.

 

So I am willing to contribute where I can .... and this has been the main reason for joining this site.

 

What is NOW becoming evident to me is the opportunity - by way of patient's own informal interchange, to self inform and help THE TRANSPARENCY OF A PATIENT RESOURCE DEVELOP.

 

.....

 

 

 

But seriously, there is still so much that is undefined concenring auto immune connection and especially where there are multiple gut sensitivites and general inflammatory diease manifesting elsewhere in the body ....

Afterall the circulatory sytem can not be isolated .....

 

And my own involved med history is a case in point - especially once the bowel perforated .....  There is a complicated history of joint disease and damage ..... And in my case  Crohn's Disease was the 'root' diagnosis ......

 

THIS IS ONE REASON I WISH TO PUBLISH MY OWN TIMELINE PICS OF THE TIES DEVICE BECAUSE IT IS IMFORMATIVE - AND CURRENTLY THE SPONSOR COMPANY FOR TIES HAS PUBLISHED A CONRTA INDICATION FOR ANY PATIENT BASE HAVING A CHRONS DIAGNOSIS.

So far as I'm concened there is a responsibility we all have to those following us - and hence my own moral wish to publish timeline data without commentary - so that there is a pictorial reference - transparency for All to access - of my own TIES IMPLANTATION hosting of the device during Clinical Trial experiece - and also my ongoing pictorial time line pics following the device's explanation - For it is insufficient IMHO for just Trial Data to be recorded up to explantation ..... as this is a very limited time line of investigation!  And when Clinical Single Study Closed Trials are used - there is little to NO Transparency for the Public to access the research data.

 

 

 

When I was first diagnosed with CD as a young woman late teens and had my own 'experimental treatments, as my family chose to delay surgical intervention whre infection was clearly prevalent .... We did not KNOW then,, but I long suspected that Cd had genetic elements involved .... and so, personally made the decision not to have children.

What I have tried to do in my own medical path is always to be open to possibilities and have contributed where I can to R+D and have remainined in touch with my various Clinitiacians.   Perhaps in so doing there may be a slightly more informed line of reference that may inform.

 

So I am willing to contribute where I can .... and this has been the main reason for joining this site.

 

What is NOW becoming evident to me is the opportunity - by way of patient's own informal interchange, to self inform and help THE TRANSPARENCY OF A PATIENT RESOURCE DEVELOP.

 

.....

 

 

 

Afterall the circulatory sytem can not be isolated .....

 

And my own involved med history is a case in point - especially once the bowel perforated .....  There is a complicated history of joint disease and damage ..... And in my case  Crohn's Disease was the 'root' diagnosis ......  WHICH COMES RIGHT TO THE HEART OF YOUR QUESTION - what autoimmune related stuff has a bearing on other manifestations of our chronic conditions as we continue to manage ourselves.

 

I am no medic - and am also aware that a 'little knowledge' of what we think we may know [with a little k] can be a dangerous thing upon which to base any lasting decision - but IMHO we can , and should try to be open to informing ourselves and others and where possible may available such ino that could have relevance to those WHO ARE reseaRCHING From a MEDICALLY AND A Med-tech Perspective , and in so doing help inform - particulalry now that AI can actually correleate info ...... and also acutually - through proper citation - begin to form a more cohesive undersnding ..... which, hither to has been somewaht fragmentary.

 

I find your own posts Jodie, and those of others who contitibute medic fact so far as patient experience is concerned, an invaluable sharing - ANd I very much hope, that the exceptional cross fertilisation of info that is now possibole will be AID UNDERTSNADING AND ACCURATE TRANSPARENT RESEARCH GOING FORWARD.

 

THIS IS ONE REASON I WISH TO PUBLISH MY OWN TIMELINE PICS OF THE TIES DEVICE BECAUSE IT IS IMFORMATIVE - AND CURRENTLY THE SPONSOR COMPANY FOR TIES HAS PUBLISHED A CONRTA INDICATION FOR ANY PATIENT BASE HAVING A CHRONS DIAGNOSIS.

So far as I'm concened there is a responsibility we all have to those following us - and hence my own moral wish to publish timeline data without commentary - so that there is a pictorial reference - transparency for All to access - of my own TIES IMPLANTATION hosting of the device during Clinical Trial experiece - and also my ongoing pictorial time line pics following the device's explanation - For it is insufficient IMHO for just Trial Data to be recorded up to explantation ..... as this is a very limited time line of investigation!  And when Clinical Single Study Closed Trials are used - there is little to NO Transparency for the Public to access the research data.

I HAD EXTENSIVE REACTIONS WHICH HAVE TAKEN MANY MANY MANY MONTHS TO HEAL

CROHNS DISEASE IS AN AUTOIMMUNE DISEASE WHERE THERE IS STILL A LOT OT BE DISCOVERED

....

 

Maybe we can all help in some small way to help inform the bigger picture :-)

 

 

BW

Jayne

 

PS

Sorry my posts become a little heavy at times - I work with a very slow broad band connectivity and often loos my cut and pastes when trying to edit a post live online .... So if I have repeated myself and am dis-jointed in my words please forgive ....

I will come back and re-edit where appropropriate - as best as I am am able.

TY for folks understanding - I know I am not the most concise person on here ;-(   [I do try and readthrough - but not always at the time of keying].

J.

 

PPS:

Jodie, you may like to paste this in to a search:

Altered Bioavailability and Pharmacokinetics in Crohn’s Disease: Capturing Systems Parameters for PBPK to Assist with Predicting the Fate of Orally Administered Drugs

Quite a bit of my own treatment regeimes involved experiementation with different pharma applications - and it seems to me that as pharma develops - alongside, of other more holistic understanding - there is mileage in Patient consideration of what may at first appear to be tenious associations - for when one does interchange with research chemists and Others with specialist understanding our own understanding of our bodies and our musings can actually be valid and are not so dissmissable as first they may appear.

J

Axl

Nope

CrappyColon
Reply to Jayne

Jayne, I read Australian scientists are working on developing a vaccine for Strep A (precursor to scarlet fever) 😀

CrappyColon
Reply to w30bob

Ya. sounds like your second uncle Vinny (seriously, what’s a second uncle??) and I would’ve been besties. 

Jayne
Reply to CrappyColon

Jodie,

OK, .......  So no scarlet fever vaccine - I was mistaken ....

I'll edit my earlier thought so as not to confuse folk .... Thanks Jodie

BW

Jayne

Jayne

SORRY FOLKS

It seems I have scrambled my edit - or the software is pasting my edit in odd places ......

I will return later to simplify   !!!!

Hisbiscus

They think I may have some autoimmune disease. Many strange symptoms over the years and skin cracking severely.im hoping for me that I can finally get an answer to all of this. 

I think these autoimmune disease can cause many issues before they find out what it is. It causes our systems to be super sensitive and weakens our immune system. So maybe why you got the Scarlett fever?

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