Mars1954, I have also had problems with itchy, burning skin, sometimes under tape, sometimes under garments that are too tight, like most of my socks. For the tight garments or latex, I have no answer. Yes, it is possible to develop a sudden allergy to a food or product that you have used for years, especially if you have some kind of autoimmune disorder like cancer. For the tape or flange adhesive problems, I have just started using a powder made by Convatec that becomes a skin barrier and adhesive at the same time. Also, it is easy to wash off and reapply when changing bags. The secret is to apply it liberally to the area where the adhesive will touch the skin then using a dry tissue dust it off until you can barely see a thin coating of it on your skin. Then apply the tape or flange directly to the dry powder. I have a colostomy, not a colostomy, but these problems are common to almost all stomachs.