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Oct 11, 2023

Chemotherapy Absorption Concerns with an Ileostomy

This topic is about a person who has been living with an ileostomy for 25 years and is starting a new cancer medication called Cabometyx. They are concerned about whether the drug will be fully absorbed before it exits through their stoma, especially since it might be a time-release tablet. The oncologist isn't familiar with these specific concerns, so the person is looking for advice from others who might have faced similar situations.

Here are some helpful suggestions:

1. Talk to a pharmacist or chemist as soon as possible. They can provide information about how the drug is released and absorbed, and whether there are alternative forms like liquid, chewable, or crushable options.

2. Reach out to the prescribing oncologist to discuss your concerns about absorption. Ask for clarification or request an alternative form of the medication if needed.

3. Whenever you are prescribed a new medication, remind your healthcare provider about your ileostomy. Specifically ask if the medication is available in a liquid or chewable form to avoid time-released or enteric-coated tablets that might not be absorbed properly.

4. Keep your medication list current and ensure that any changes, including discontinued drugs and details about your ostomy, are accurately recorded in your electronic health record. This helps prevent receiving medications that might not be suitable for you.

5. One person shared that they completed chemotherapy 23 years after their ileostomy without any absorption issues, indicating that some systemic drugs can still be effective. However, it's important to verify this on an individual basis.
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