The topic explores the exciting possibilities of bio-engineering or transplanting a new colon for people with ostomies. Inspired by advancements like growing ears and bladders from a patient's own DNA, the discussion delves into whether a fully functional colon could be next. While the original poster is skeptical about seeing this in their lifetime, they hope future generations might benefit. Here are some insights and advice shared in the discussion:

1. Current experimental work:
- Scientists have successfully grown "organoids" or mini-organs for skin, bladder, heart tissue, and even an external ear on lab animals.
- Pigs are being studied as potential sources for organ transplants due to their similar organ size to humans. Researchers are working on reducing rejection by removing antigenic factors.

2. Technical obstacles to a colon transplant or implant:
- The colon's role is not just to move stool; it also reabsorbs large amounts of water and electrolytes, which a simple plastic tube cannot do.
- A successful transplant would require complex reconnections of blood vessels and nerves; without these, the organ wouldn't function.
- Previous abdominal surgeries can create scar tissue, increasing the risk of damaging pelvic nerves during further operations, which can affect sexual function.
- Pig-to-human transplants carry the risk of transferring parasites that humans have no immunity against.

3. Experiences with bowel reconstructions and reversals:
- Some people have experienced severe issues post-reversal, such as inflammation, frequent acidic discharge, pain, weight loss, or incontinence.
- Others have had positive outcomes, showing that results can vary greatly. Thorough pre-operative evaluation and realistic counseling are crucial.

4. Ethical and regulatory considerations:
- Therapeutic cloning and embryonic stem-cell research could potentially provide rejection-free intestinal tissue, but progress is slowed by U.S. federal restrictions and opposition from some groups.
- Cloning for spare parts raises significant ethical concerns, as a genetically identical donor would still be a human being.

5. Practical advice to patients:
- It's important not to rely solely on one surgeon's opinion. Seek second opinions and ask detailed questions about function, lifestyle impact, and risks to sexual nerves before agreeing to reversal or transplant trials.
- Stay informed about new research by checking credible medical journals and major research hospital websites.