The topic at hand is about dealing with irritated skin under an Eakin seal, which is a common concern for those using ostomy appliances. The person experiencing this issue has noticed that the irritation hasn't improved even after changing their appliance. They have considered using Zincofax diaper-rash cream but are seeking advice before proceeding.

Here are some helpful suggestions and insights:

1. Consider having a physician take a swab of the irritated area to determine if there is a bacterial or fungal infection. This will help in choosing the right treatment.

2. Visiting a wound-care or ostomy clinic can provide professional assessment and recommendations for suitable products to use.

3. If a fungal infection is suspected, Nystatin can be used in either ointment or powder form. Both require a prescription.

4. For cases of infection or severe inflammation, Desoximetazone gel is recommended as it dries quickly and stays in place under the barrier. This also requires a prescription.

5. Be aware that both Nystatin and Desoximetazone might need to be specially ordered from the pharmacy if they are not readily available.