Topic Explanation
The discussion in the forum revolves around the effectiveness and safety of new weight loss drugs for patients with a permanent ileostomy. The original poster is seeking insights from others who have tried these medications to understand if they are absorbed normally and work effectively for individuals with an ileostomy.

Advice and Insights from Replies
1. Experience with Specific Drugs:
- One user shared their experience with Ozempic, noting initial side effects like upset stomach and runny stools which settled after a few weeks. They highlighted the use of Imodium to manage diarrhea, a common side effect, and mentioned that weight loss was moderate (25 lbs lost), emphasizing the importance of diet and exercise in addition to medication.

2. Concerns and Warnings:
- Several users expressed skepticism about the effectiveness of weight loss drugs, noting that the weight loss might not be as significant as advertised and could rebound after stopping the medication.
- Concerns were raised about potential severe side effects such as dehydration, kidney problems, and the risk of a "frozen intestine" or severe blockages, especially for those with only a small intestine remaining.
- The use of Imodium was specifically cautioned against by one user, citing cases where it led to hospitalization due to its mechanism of paralyzing the intestines.

3. Alternative Approaches and Precautions:
- One user mentioned being referred to a dietitian-led course and an exercise protocol to manage weight and blood sugar levels, suggesting a more holistic approach to weight management.
- The use of Berberine was discussed by two users; one considering it to help with blood sugar management and another using it in small doses to aid in feeling full, though caution was advised regarding its dosage and potential side effects.

4. General Advice:
- It was recommended to consult with endocrinologists and gastrointestinal doctors before starting any new medication, especially to understand the specific risks associated with ileostomy patients.
- Personal anecdotes highlighted the importance of managing expectations and being cautious of the side effects related to weight loss medications.