This topic is about dealing with a persistent peristomal infection, which is an infection that occurs around the stoma site. The discussion focuses on a specific case where an ileostomate had a stubborn infection and the treatments that were used to heal it. Here are some insights and advice shared:

- An ileostomate had a 3" × 2" infected lesion beneath the wafer. The surgeon confirmed it was a common soft-tissue infection that usually doesn't spread under the abdominal muscle, so no surgery was needed.

- The first treatment involved a 7-day course of two strong oral antibiotics, which slowed the drainage but didn't stop it completely.

- The second treatment was the application of Iruxol cream for several weeks, which reduced the lesion size, but a small section remained moist.

- The final treatment was Neobol spray, which helped form a dry layer of new skin, and the wound finally closed.

- It's important to see a clinician for prescriptions.

Here are some additional tips and insights:

1. Neobol Availability and Composition:
- Neobol is not available in the USA or Canada. It contains Clostebol Acetate and Neomycin Sulfate. A similar product exists in the U.S. but is for veterinary use only.

2. If Neomycin Allergy or No Infection:
- Neomycin can cause allergic reactions, so dermatologists might avoid it. An alternative is using the steroid component only, like spraying Symbicort inhaler on lesions.

3. Drying and Cleaning Weepy, Non-infected Sores:
- Use gauze soaked in Domboro solution as a compress during appliance changes. Medihoney can also promote healing under the dressing.

4. Managing Itchy or Irritated Peristomal Skin:
- Minimize barrier wipes and use adhesive remover during changes. Zinc-oxide cream can help with red bumps. Clean skin with diluted zinc-containing dandruff shampoo. Alternatives for light barrier layers include aloe-vera gel, Milk of Magnesia, or Povidone-Iodine. Natural Care Gel is soothing, and silicone-based adhesive removers are preferred.

5. Steroid Sprays:
- Prescription-strength topical steroid sprays can be used instead of inhalers, but limit their use to avoid thinning the skin.

6. General Tips:
- Take photos of lesions during changes and send them to your healthcare provider for assessment. Review all ostomy products, as itching might be due to changes in wafers or accessories.