This topic is about dealing with itching and blister-like irritation that can occur under a Hollister one-piece ostomy pouch. The person experiencing this issue has been using the pouch without leaks for two months but starts to feel discomfort a day or two after changing it. They have tried switching to a smaller pouch, but the problem persists, and they are seeking advice on how to stop or heal the irritation.

Here are some suggestions and insights that might help:

1. Try using a steroid metered-dose inhaler, like those used for asthma, and spray it directly on the rash. It dries quickly, leaves no greasy residue, and doesn't affect the pouch's adhesion. This method has been found to be more effective than steroid creams.

2. Consider the possibility of a contact allergy or sensitivity:
- Experiment with different brands or systems, such as Coloplast one-piece, Coloplast two-piece, or Convatec two-piece, which has a soft, fabric-like adhesive flange.
- Request free samples from manufacturers and test them systematically to find a suitable option.

3. Contact Hollister’s customer-care line. They are known to be helpful with troubleshooting and can offer product alternatives and tips.

4. Review your removal technique. Pulling the wafer off might uproot tiny hairs, causing stinging or itching. Consider trimming or removing hair or using adhesive remover wipes.

5. If a fungal component is suspected, consult your physician about using an antifungal/steroid combination cream. Apply it, let it absorb, and then cover with a generous layer of skin-prep barrier before applying the pouch.

6. If symptoms persist or if psoriasis is suspected, see a dermatologist. Medications like Stelara (ustekinumab) have helped others with similar skin issues.

7. Consider a dietary link. Some people notice worse itching after consuming high amounts of sugar. Reducing sweets might lessen symptoms.

8. If commercial wafers continue to irritate, try a DIY approach. Create custom-shaped baseplates held by one or two belts, and secure the pouch with a light mist of medical adhesive spray. Users have reported long wear times and no irritation with this method.