Taking imodium?

Replies
30
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599
HenryM
Jun 10, 2025 9:49 am

I'm seeking comments from anyone with experience taking OTC Imodium (loperamide) to reduce wateriness of stool.  How well does it work?  Does it thicken output too much?  How much and how often do you take it?  Any side effects?  My goal would be to reduce the prospect of dehydration from losing so much liquid in discharge.  Appreciate any feedback.  Thanks.  

Mrs_Eff
Jun 10, 2025 11:28 am

Hey there, Henry. I have taken loperamide for many years, and it really does help to thicken up your output. I generally take one a day (10 mg), which reduces the water content, but this won't help you with dehydration. You will still need to stay hydrated and make sure you're taking liquid on board regularly. I have had absolutely no side effects whatsoever, but I would recommend you speak with a healthcare professional if you're at all worried. It is one of those medicines you could try and see how you get along with.

ron in mich
Jun 10, 2025 12:43 pm

Hi Henry, I take one Imodium after breakfast, and that usually does it for me, but it also depends on what I eat. Also, if I'm going to be away from the house for a couple of hours and eat a later dinner, I will take a second one.

IGGIE
Jun 10, 2025 1:45 pm

Henry, wouldn't you still be losing the same amount of liquid? You're just thickening it up.

IGGIE

Axl
Jun 10, 2025 1:47 pm

Funny you should bring this up now, Henry. I have just started the same three days ago. I have done a little research here with people's experiences and am taking one 2 mg mid-morning and one 2 mg about 3 or 4 in the afternoon, and so far the results are good.

 

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infinitycastle52777
Jun 10, 2025 2:13 pm

I can take it up to 3 times a day. But I don't often take it. I took it when I went on a trip a while back to slow down the output and thicken it up. It did just that. Worked great. I took it a lot when I first had my ostomy to thicken up output because I had such large amounts of liquid output. It did the job then too. I have it by prescription now. But I haven't had to fill the script in some time now. I mostly only have liquid output at night now. In the daytime, things say semi-thick. So I don't worry about it too much. I drink plenty of water and electrolyte drinks to keep hydrated.

Ben38
Jun 10, 2025 2:23 pm

I don't take them very often now, but for high output, they're a lifesaver and non-addictive. Fast-acting, so even if you were to take too many, it would wear off in hours. Start with a low dose, just 1; if that makes no difference, take 2. It's best to take them between 1 hour or 30 minutes before eating, depending on how fast your output is. Then it's just seeing how it goes, whether you need to take them once a day or 4 times.

cjotl2019
Jun 10, 2025 8:46 pm

Imodium slows down your gut motility. Try eating foods that thicken up your stools, like mashed potatoes, bananas, applesauce, pasta, marshmallows, rice, and toast. I truly believe I was taking too much Imodium because I got a blockage, and my motility was slowing down so much that nothing worked. I was taking two, two mg tablets four times a day.

SusanT
Jun 10, 2025 11:20 pm

I tried it, but it doesn't do much for me.

Hugo
Jun 11, 2025 1:49 pm

Imodium works great for me. I have a very high-output colostomy. I take 2 mg tablets in the morning and 2 in the evening at least half an hour before eating. I still get a lot of output, but it is more formed and much easier to deal with and a lot less messy. I can wear the same pouch much longer without changing it. I consulted with my WOC nurse about taking it, and she said it was perfectly okay and safe to take it, at least for me.

warrior
Jun 12, 2025 1:09 am

My sentiments exactly. It's a game changer. Just try it and see what amount is a good balance.

Remember you have to drink more fluids while taking this, too.

What will Henry decide?🤔

drsnickers2
Jun 14, 2025 2:34 pm

My GI suggested that I take a level teaspoon of Metamucil each morning, and yeah, it really helps thicken my output.

kevinrvs1
Jun 14, 2025 8:25 pm

Hi

I've been taking Imodium for years. You will need to find the right dosage and frequency for your individual metabolism, but once you do, you should be fine. Just remember to leave at least 30 minutes between eating and taking your tablets; otherwise, the tablets will likely have the opposite effect to that wished for.

dubber365
Jun 15, 2025 4:46 am

Hey Henry.  I never heard of taking Immodium to thicken output?  I’ve had mine about 4 years.  I was told to eat gummy bears or any gummy candy or marshmallows if it is watery.  If it’s real thick, it’s harder for me to empty.  Mine is different every day.  I guess depends on what you eat or drink.  It can be watery, then thicker.  I use baby oil in the pouch to keep it easier to empty.  Try gummy candies.  

Chiquis
Jun 15, 2025 5:04 am

I took immodium like every 8 hours and saw very little difference.  Try marshmallows. 

jambly405
Jun 15, 2025 5:11 am

Hi Henry. I have taken Loperamide Hydrochloride for a long time. I was discharged from hospital with a high output stoma and was prescribed 24mg of Imodium and an ORS rehydration mix as well. A few years on I now only take 4mg of Imodium which I find is enough to control the output. you may have to experiment to find the right dosage for you.

I'm not aware of any side effects, but we are all different in this respect. I would say that it is more important to keep hydrated than risk injury to the kidneys which can happen if a watery output is experienced over a long period.

Imodium is highly effective and works by slowing down the gut which then allows the small intestine to absorb more water and essential salts into the blood stream rather than speeding through into the bag.

harapavlou320
Jun 15, 2025 6:23 am

Hi,I take imodium, 3 tablets half hour before food,it doesn't make it very thick & I'm glad I take them 

Without it's just green water 

shananigans
Jun 15, 2025 2:43 pm

Hello all, just wanted to add that I take one pill at bedtime to help ensure not being awakened by an active gut in the middle of the night. Has helped a lot. Appreciate all your experiences--may try it in the day as well. Thanks

rlevineia
Jun 15, 2025 3:08 pm

Henry.  I hate watery output!  Mess to empty, worst to change pouches.  A few mths ago I altered my diet.  I eat potatoes with dinner & low salt pretzels & cookies, the nite before I change.   Still drink 8 glaases a day.  Eat 4 marshmellows 45 mins before changing pouches.  Rest on your back for a few minutes prior to change, to slow peristalsis.  Like squeezing out putty.  Instead of 8-10 wipes per clean up, only 0-2 wipes.

trina.rosecat
Jun 15, 2025 3:27 pm

Hi there, I'm dealing with dehydration too. I've started taking Imodium and appreciate the shared experiences here. I am taking salt supplements but it's a tricky balance with electrolytes. I'm so tired of feeling so tired. I've heard of people going for IV fluids every week and I'm trying to organize that for myself. 

debbiedeeds1
Jun 15, 2025 5:59 pm

I take Imodium everyday upon advice from my gastroenterologist.  In the beginning I took up to recommended dosage.   Now that my output is at an applesauce consistency I take one in morning and one at night

debbiedeeds1
Jun 15, 2025 6:00 pm

I take the ultima electrolyte in my water all the time. 

thegonzos1
Jun 15, 2025 8:30 pm

Me too!

stirrednotshaken
Jun 15, 2025 8:41 pm

Same here.   I take 4mg 4 times a day along with lomotil and can’t really tell if it does anything, but am afraid to stop in case it does.

Wink
Jun 15, 2025 10:34 pm

I have been taking OTC Imodium on and off for two months with mixed results.  My output is extremely watery, and sometimes it thickens it up, not too much, and other times it doesn’t seem to have any effect.  I take it just before I eat a meal, about 15ml per dose.

If you take it, have your doctor prescribe it for you and your insurance could pick it up and save you the high price of the OTC. Good luck!

IGGIE
Jun 16, 2025 1:40 am

To help with Electrolytes I find that drinking Coconut Water is tasty and does the job.

Regards IGGIE

almelia
Jun 16, 2025 6:46 am

I was becoming very dehydrated the first summer after surgery. The hospital prescribed 2mg imodium/ loperamide upto 8 tablets per day plus rehydration salts to add to fluids. ( They told me they had a patient on 32 tablets per day!) .

I only take them rarely now but always carry some with me.

Amac
Jun 16, 2025 8:13 am

Hi Henry

My stoma nurse advised me to take immodium 20 to 30 min before a meal, and to take it in tablet form not the capsules as the tablet dissolves better, the pack will advise no more than 4 per day but I can have very watery output so I am taking 2 per meal and possibly 1 before bed, but I would agree with others that some food types will help thicken our output (or loosen). I was also advised to use salt on almost everything as it will increase your fluid intake.....colonostomy user 2yrs ileostomy user 8 months waiting for reversal ....living as good as I can and going hiking in the Italian/Swiss alps in 2 weeks loads of immodium being packed 

NC Osteo
Jun 16, 2025 10:35 am

Henry, I have a ileostomy and take an alternating daily regiment of OTC Imodium and lomotil to slow and thicken output. I take 30ml liquid Imodium, 4 times a day but will adjust both medicines if output is getting too dry which is rare.  The Imodium works better, imo, than lomotil to slow/stop and thicken output. For me it’s a necessity to allow body to absorb nutrients through reduction of ostomy liquid output.  Good luck in your efforts. 

k9rulz
Jun 16, 2025 9:54 pm

Henry, I have an ileostomy (I forget if you do too), after total colectomy, so all the warnings for Immodium no longer apply. According to my GI doctor/surgeon, I can take one or two tablets before meals and before bedtime (so 4 to 8 total) per day. This has really helped me reduce my liquidy output and helped with leakage, which is more due to my poorly formed stoma that is partly flush with my belly that requires a convex bag. I had gotten a lot of advice from everyone on here when I first got out of the hospital, and it was a great help, so anytime I can offer my meager advice, I do what I can :). 

Also, if your insurance will pay for it (mine does) get your doctor to write an RX for lopermide - one, it's cheaper that way (for me at least); two, you don't have to futz with the annoying safety blister packs that OTC lopermide comes in, which makes a HUGE difference if you're consuming 4-8/day!

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