The topic at hand is whether the immune system is compromised after the removal of the colon. This is a concern for those who have undergone such surgery, as the colon is known to play a role in immune function. Here are some insights and advice on this topic:

1. **Immune System Concerns**
- The removal of the colon might affect immunity, but the body has other defenses like stomach acidity and immune tissues elsewhere that continue to fight pathogens.
- If you're worried about your immune system, consulting an immunologist could be helpful, though regular lab work often provides enough information about your immune health.

2. **Hydration and Electrolytes**
- Without a colon, your body absorbs water less efficiently, so it's important to drink more fluids to avoid dehydration and kidney stones.
- Adding extra sodium to your diet can help, as sodium absorption usually happens in the colon. Some also suggest adding lemon to water to reduce kidney stone risk.

3. **Nutrition and Supplements**
- Taking a routine multivitamin can be beneficial, especially for those with long-term ileostomies.
- Eating a balanced diet and being mindful of foods that cause gut issues can reduce the need for additional supplements.
- A GI absorption chart can help identify potential vitamin and mineral gaps.

4. **Laboratory Monitoring**
- Regular blood tests, including CBC, liver and kidney function, and electrolytes, are recommended.
- To check immune status and inflammation, monitor white blood cell count, immunoglobulins, and C-Reactive Protein (CRP).

5. **Lifespan and General Health**
- Many people live 30 to 50 years or more with ileostomies and report normal lifespans.
- Some individuals feel healthier after surgery than they did before, even as they age.

6. **Microbiome Considerations**
- The colon hosts a significant portion of the microbiome, which helps synthesize vitamins and supports immunity. Its removal may reduce these benefits.
- There is speculation that processed foods, chemicals, and GMOs contribute to IBS/IBD, but evidence is not conclusive.

7. **Genetics vs. Environment**
- The role of genetics and environment in conditions like UC and Crohn’s varies. Some families have no history, while others do, suggesting both genetic predisposition and environmental triggers may play a role.

These points provide a comprehensive look at the potential impacts of colon removal on the immune system and overall health, along with practical advice for managing these changes.