This topic is about finding medication options to help manage gas and ballooning in an ileostomy pouch, especially for someone dealing with both chronic kidney disease and short-bowel syndrome. After many years without issues, the person has started experiencing severe gas, which has even caused a night-drain bag to burst. Due to their health conditions, they are looking for medication solutions rather than dietary changes. Here are some suggestions that might help:

1. Simethicone Softgels
- Consider using Kroger Ultra Strength Gas Relief, which contains Simethicone 180 mg. Make sure the box says "Kroger."
- Gas-X Softgels also contain the same active ingredient.
- You can either swallow a capsule or pierce the softgel and squeeze a few drops into the pouch. Many users find relief from gas within about 15 minutes.

2. Enzyme Tablets
- Products like Beano, which contain alpha-galactosidase, can help prevent gas from forming. These might be more effective than simethicone for some individuals.

3. Mechanical Venting Aid
- The Osto-EZ-Vent is an adhesive vent that can be applied to any pouch to release built-up gas. There is also a deodorizer attachment available.

4. General Tips
- Avoid chewing gum to reduce swallowed air.
- Chew food thoroughly to minimize the amount of air swallowed.