This topic is about managing the use of Prednisolone, maintaining bone health, and caring for a colostomy while treating Polymyalgia Rheumatica (PMR). Here are some insights and advice shared by individuals dealing with similar situations:

- A forum member, who has had a permanent colostomy since 1983 due to rectal cancer, generally manages well. They sometimes use irrigation to remain bag-free for up to 36 hours, especially when traveling.

- Six months ago, this member was diagnosed with PMR, a condition expected to last 2-3 years.

- Their current medications include:
1. Prednisolone, which started at 20 mg daily and is now reduced to 15 mg, to be continued at least until June.
2. Calcium carbonate combined with Vitamin D.
3. Alendronic Acid, a bisphosphonate, is prescribed because Prednisolone can deplete calcium from the bones.

- There are some uncertainties regarding:
1. The long-term effects of Prednisolone on the remaining bowel or colostomy.
2. Side effects beyond mood swings and hair loss.
3. Whether anyone with PMR or Giant Cell Arteritis (GCA) has successfully used an alternative to Prednisolone.

- The member explains that irrigation, performed initially under medical supervision, allows them to go bag-free for 36 hours, though it may not be suitable for everyone with a colostomy.

- They are interested in hearing from others with PMR who might be using a substitute for Prednisolone.

For those concerned about bone health while on steroids, here are some important points:

- Long-term use of Prednisolone, whether orally or as Predsol® enemas, can lead to serious osteoporosis, even in younger individuals.

- It is crucial to take daily supplements of calcium and Vitamin D.

- Discuss with a knowledgeable physician about adding or continuing a bisphosphonate like Alendronic Acid, as these drugs can have their own side effects but are important for bone protection.

- Reducing alcohol intake is advisable, as it can further increase the risk of fractures.

- One member shared their experience of receiving IV steroids for a year without noticeable side effects but continues to take daily calcium and vitamin supplements as a precaution.