CO2 Treatment for Adhesion Separation Before Surgery?

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Jayne
May 30, 2025 7:38 pm

Does any Patient Member / Surgeon Member of the Site have experience with the specialist use of Carbon Dioxide treatment - prior to interventive abdominal surgery - to aid adhesion separation?

I am currently researching information concerning such potential 'easement' which may be proposed prior to undergoing further surgical intervention around the stoma/small bowel and the abdominal wall/musculature [behind the abdominal wall but outside of the peritoneal cavity]?

Any information - related discussion would be appreciated.

It is difficult for a non-medical / non-biotech trained person [me] to follow the science when researching - any observations from any informed professional or from any patient who has actually received such a pre-operative treatment [probably for complex hernia surgery or abdominal wall/complex bowel surgery] may be able to comment?

I lack the understanding to differentiate between the potential good application of this and what may appear to be contraindications ...

https://pmc.ncbi.nlm.nih.gov/articles/PMC3609691/

Thank you

Jayne

Axl
May 31, 2025 5:03 am

I'll go first; I've never heard of it, and it's a bit complex for me.

 

https://pmc.ncbi.nlm.nih.gov/articles/PMC3609691/

 

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Bill
May 31, 2025 7:00 am

Hello Jayne.

Thank you for providing a link to the study.  These types of specialised studies are not easy to read through and the most significant aspects are often hidden amongst the prolific detail.
For me, the suspect ethics of killing animals in experiments (see how many died and were excluded from the statistics) speaks volumes about how these people view the value of life.
In the study summary,  there is a brief mention of:    "CO2 did not trigger any significant effect nor interactions, irrespective of its insufflation before or after sidewall adhesion model-induction". 
Which means that, as far as being of any practical use, it would seem to have none whatsoever.
The far more significant outcome in this study is given scant credit. That is the high death rate involved in experimentation of this sort.
Beware !
Best wishes

Bill

SusanT
May 31, 2025 1:02 pm
Very helpful

Thanks Axl for reposting the link as a working link. I was feeling lazy.

Jayne: This study aimed to see if the introduction of CO2 during surgery could prevent adhesion formation.

They found some differences in the site and type of surgery, but no differences based on the use of CO2. It was a failed experiment.

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