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Sep 24, 2021

Slow-release Medications & Ileostomy - Absorption Concerns?

This topic is about the challenges of absorbing slow-release medications after having a loop ileostomy. A person who recently had this surgery is concerned that their medication, Effexor XR, might not be absorbing properly, which could affect their anxiety treatment. They noticed that other slow-release medications were not being absorbed and are seeking advice on what to do.

Here are some helpful insights and advice:

1. Extended-release or time-release medications often do not absorb well in people with an ileostomy. It's generally recommended to avoid these forms.

2. Consider asking your doctor for an immediate-release version of your medication, a liquid form, or an intravenous option if you're still in the hospital.

3. If you only have capsules, you can open them and mix the contents with applesauce or water. However, be aware that this might affect how the medication is released in your body.

4. Do not crush or open tablets that are specifically designed for slow release without consulting a healthcare professional, as this can lead to a sudden release of the medication, which might be harmful.

5. You can perform a simple test at home by placing a pill in a glass of water. If it doesn't dissolve in 30 minutes, it might pass through your system without being absorbed.

6. Some doctors might adjust the dosage by splitting the total daily dose into smaller amounts taken more frequently, rather than altering the form of the medication.

7. To confirm whether your medication is being absorbed, a blood test to measure drug levels can be helpful.

8. To slow down the movement of your gut and improve absorption, take once-daily medications with your evening meal and lie down afterward. You can also use a pill-splitter for large immediate-release tablets to help them dissolve faster.

9. Always consult with a pharmacist who is knowledgeable about stomas when starting a new medication. They can work with your doctor to find the best formulation for you.

10. Be proactive in your care. If you have concerns, ask to speak with an on-call physician who can make immediate adjustments to your medication orders.

Some of the medications mentioned include Effexor XR (venlafaxine ER), Flomax (tamsulosin slow-release), Cipro (ciprofloxacin), and Flagyl (metronidazole).
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