This topic is about the medication Pristiq (desvenlafaxine), which is an extended-release antidepressant. The concern is whether it will be absorbed properly in people who have an ileostomy, as they do not have a colon. Here are some helpful points to consider:

- Check with a pharmacist to confirm where Pristiq is absorbed. It's important to know if it relies only on the small intestine or if the large intestine is also involved.
- Consult with a pharmacist or your doctor for advice tailored to ileostomy patients. They can look into the manufacturer's information if they are unsure.
- Think about how much of your small intestine is left. If a large part has been removed, it might affect how well the medication is absorbed.
- Talk to your doctor about other antidepressant options. For example, Effexor (venlafaxine) comes in an immediate-release form, which might be a better fit if extended-release medications are a concern.