This topic is about a person who has had an ileostomy for four years due to Crohn’s disease. They are taking 32 mg of loperamide and 40 mg of omeprazole daily to manage high stoma output. Despite this, they have lost a significant amount of weight and feel constantly tired, even though their blood tests seem okay. They are wondering if omeprazole or related sleep issues might be causing their fatigue and are seeking advice on alternative medications or solutions.

Here are some helpful insights and advice:

1. High stoma output can lead to chronic dehydration, which often results in fatigue. It's important to review your fluid and electrolyte intake to ensure you're staying properly hydrated.

2. Consider checking your vitamin B12 levels. People with an ileostomy often become deficient in B12, and low levels can cause significant tiredness.

3. The autoimmune nature of Crohn’s disease itself can contribute to fatigue, and medications can have side effects. It's a good idea to assess all your current medications, not just omeprazole.

4. Routine blood tests might appear normal, so it could be beneficial to request a full micronutrient work-up along with standard labs to get a more comprehensive view of your health.

5. Severe or prolonged dehydration can lower blood pressure, leading to dizziness and exhaustion. You might want to consider monitoring your blood pressure at home.

6. Explore forums and discussions for recent threads on omeprazole and hydration strategies. These can provide valuable insights and shared experiences from others in similar situations.

7. Improving hydration management can involve a tailored diet, possible medication adjustments, and learning stoma-specific techniques. Since experiences vary, it may take some experimentation to find what works best for you.